Saturday, April 11, 2015

Post Number 7


Unlike Chronic Lymphocytic Leukemia (CLL), Acute Myeloid Lymphoma (AML) does not affect just older individuals. It is the most common form of leukemia in adults and has similar symptoms to CLL, but is not a chronic disease so it frequently targets young adults (ages between 20 and 40). At the clinic, there a man in his thirties had been diagnosed with an aggressive form of AML. At first, doctors decided to use the wait and watch method to see if the disease worsened. Eventually, they decided that the best form of treatment to use was a stem cell transplant. During the appointment, they discussed possible donors and chemotherapy treatment needed after the procedure to help him recover from the stem cell transplant. The man was told that the drugs necessary for his treatment would most likely harm his ability to reproduce, and as you can imagine, he and his wife did not take the news happily. Of all the patients with difficult stories that I have been able to meet, this patient’s dilemma was the most impactful because of how young he was. Watching a new, young couple being told that they may not be able to have their own children put me in a state of sorrow like none of the other patients’ stories had.

As for the evaluation of the treatment for the patients with Relapsed/ Refractory CLL, the two patients’ data is enough to know how long the treatment process is. One patient was unfortunately unable to complete treatment, so the study is only of two patients. Both patients are female over the age of 65 that were diagnosed with CLL from two to three years ago. The first patient’s White Blood Cell (WBC) count never reached the level of the second patient, yet had much more swollen lymph nodes. Patient one was previously diagnosed with Small Lymphocytic Leukemia (SLL) in 2003, yet returned in the form of CLL. Her treatment began immediately due to the occurrence of symptoms like weight loss and lymphadenopathy. Although patient two’s WBC count was twice as large as patient one’s, her treatment started a year after diagnosis because she did not have extreme lymphadenopathy. The two patients’ treatment is continuing, yet as of now patient one has had a partial response to the novel treatment and patient two had a complete response to the treatment.

Thank you all for taking time to read my blog. Again, if you have any questions, please leave a comment. Otherwise, have a great day!

Sunday, April 5, 2015

Patients Always Somehow Remain Optimistic

Graft versus Host Disease (GVHD) is a disease that comes from complications after a stem cell or bone marrow transplant. The donated stem cells begin to attack the recipient’s body and can lead to things like muscle weakness, yellowing of the eyes, rashes on the skin, and weight loss. A patient between the ages of 50 and 60 recently had a bone marrow transplant, and ultimately GVHD, causing him to be extremely thin and unable to raise his left leg. Another man in his seventies also had GVHD and muscle weakness/ fatigue, however he had gained weight because of his inability to exercise. Despite the side effects and pain that these two men have to endure, they were both in good spirits and had a great outlook on life. Rather than being sad about their diseases, they remained optimistic about their chances to beat their leukemia and continue with the lives that they love.

Another man between 45 and 55 had an aggressive form of chronic B-cell lymphoma and a hard time hearing either me or the doctor. Although at first he was extremely quiet, he began to talk about the things that brought him joy in his life, such as his soon-to-be wife and his high school hobbies including wrestling and football. He and I talked about sports for around 15 minutes during his appointment and I could see that he became more and more comfortable with the situation that he was in. The more and more we talked, I began to forget that he was a patient with leukemia because he spoke as if there weren’t any problems in his life. Seeing these strong minded patients persevere through their life threatening diseases with an open mind and a happy heart is truly inspiring. 

Thank you for taking time to read my blog once again. If you have any questions, feel free to leave me a comment. Have a nice day!